--- title: "Gabapentin: Uses & Side Effects | HealthAnswers" description: "Gabapentin is a medicine for neuropathic pain and epilepsy that requires slow dose titration and careful use as a controlled drug in the UK." url: https://healthanswers.co.uk/treatments/gabapentin/ robots: noindex --- # Gabapentin: Uses & Side Effects | HealthAnswers Treatments Gabapentin is a medicine for neuropathic pain and epilepsy that requires slow dose titration and careful use as a controlled drug in the UK. Written by HealthAnswers editorial team Medically reviewed by [HealthAnswers UK doctor review panel](https://healthanswers.co.uk/our-doctors/) Reviewed 3 July 2026 ## Quick answer What is gabapentin used for? Gabapentin is a medicine used to treat neuropathic (nerve) pain and, alongside other medicines, epilepsy. Doctors increase the dose slowly to reduce sedation, and the dose is adjusted for people with kidney disease because it is cleared through the kidneys. It is a controlled drug in the UK due to dependence risk, and it should not be stopped abruptly. ## Who is this page for? This page is for people in the UK who want a plain-English overview of Gabapentin, including when to seek help and what NHS care usually involves. It explains general information, not what is wrong with you personally. ## Who should skip this page? Skip this page if you need a diagnosis, a prescription, or emergency care. It cannot replace a GP, pharmacist, NHS 111 or 999. If you are in immediate danger, call 999; for urgent advice that is not life-threatening, call 111 in England, Scotland or Wales, or use your GP out-of-hours service in Northern Ireland. On this page 4 sections ## Key facts about gabapentin - Gabapentin is structurally similar to GABA but is not a direct GABA agonist. - It is classed as a Schedule 3 controlled drug in the UK. - The dose is usually increased gradually, often over weekly steps, for neuropathic pain. - Sedation and unsteadiness (ataxia) are common when starting treatment. - It has few significant interactions with other medicines. ## What gabapentin is used for Gabapentin is used to treat postherpetic neuralgia, diabetic neuropathy, and epilepsy as part of a treatment plan. It is sometimes used off-label for restless legs syndrome as well. ## How gabapentin is dosed Treatment with gabapentin starts at a low dose and is built up gradually, with the total daily amount divided across several doses. People on dialysis may need a supplemental dose after their session, since gabapentin is cleared through the kidneys. ## Side effects of gabapentin Drowsiness, dizziness and fatigue are common, especially when starting treatment or increasing the dose. Suicidal thoughts are a rare class effect reported with gabapentin, so any change in mood should be reported to a doctor. ## Gabapentin’s controlled drug status Because gabapentin is a controlled drug, prescriptions cannot usually be repeated early without a review. It should be stored safely, as it carries a risk of misuse. ## ! Important safety information for gabapentin Your GP prescribes gabapentin and reviews how well it is working after around six weeks for neuropathic pain. Call **111** for urgent advice when you are unsure what to do. ## Common questions about gabapentin Is gabapentin used for back pain? Gabapentin is not generally used for simple back pain. It is only appropriate when there is a nerve-related (neuropathic) component, such as sciatica, rather than ordinary backache. Is it safe to take gabapentin with opioids? Combining gabapentin with opioids increases the risk of dangerous respiratory depression, so this combination needs caution. It should only be done under specialist pain management guidance. What should I do if I miss a dose of gabapentin? Take the missed dose as soon as you remember, unless it is nearly time for your next one, in which case skip the missed dose. If you are stopping gabapentin after long-term use, it should be tapered rather than stopped suddenly. Can gabapentin cause swelling? Peripheral oedema, or swelling in the limbs, has been reported with gabapentin. Report any sudden weight gain or breathlessness to your GP, as these can be signs that need assessment. ## Sources - [NHS — Gabapentin](https://www.nhs.uk/medicines/gabapentin) - [NHS — Sciatica](https://www.nhs.uk/conditions/sciatica)